The side-effects of Dopamine.

It’s that time of year in Asia, the dreaded Monsoon Season, marked by rain and hot-humid weather.
Nobody feels comfortable, locals and visitors alike.

The correlated difference between locals and visitors goes parallel to Working and Semantic Memory.

Locals have Working Memory of the Monsoon Season eversince, therefore stable.
Non-Natives will have a Semantic Memory of the Season, therefore progressively unstable and worsening with time.

Anyway, this is not an article on Meteoropathy.
The analogy was meant as Icebreaker to abate academic language barriers by entering neuroscience field within my capacities.

PTSD, ADHD and Dementia present nearly identical symptoms in old age, henceforth often misdiagnosed.

Dopamine plays the deceiver between these disorders.
We must consider that Dopamine is an Enhancer first thing first.
Despite the general belief of beneficial Enhancing Performances, there are less pathologies that don’t benefit from them.

Scientists discovered that Dopamine works indirectly with the Stress Hormone Cortisol in PTSD by Brain Enhancement, in so prolonging recovery.
Dopamine Antagonists either deplete cells or block Dopamine at Receptor levels.
They mainly account for Antipsychotics originally developed for Schizophrenia and Bipolar Mania.

PTSD could be the next candidate in short effective administrations, although not without severe limitations: animal trials showed Rebound Symptoms following immediate discontinuation. Not to mention the implications on Memory and Motor Skills dependent on Dopamine.
More research is needed.

ADHD is associated with Working Memory, Dementia with Semantic-long term-Memory.
The bad news is that ADHDers have 3 extra chances to develop Dementia compared to NT s.
This is a major reason for misdiagnosis.

The most tricky scenario is undiagnosed ADHD, mistaken for Dementia in old people, which would not qualify for Cognitive Decline.

There is still no cure for Cognitive Decline.

Dopamine remains my primary focus.
Meanwhile, supplies are running out.
I can’t envision my future.